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当前位置: 首页 > 产品中心 > Other_reagents > JPT/RepliTope™ EBV (EBNA3a)/RT-EBV-EBNA3a/
商品详细JPT/RepliTope™ EBV (EBNA3a)/RT-EBV-EBNA3a/
JPT/RepliTope™ EBV (EBNA3a)/RT-EBV-EBNA3a/
JPT/RepliTope™ EBV (EBNA3a)/RT-EBV-EBNA3a/
商品编号: RT-EBV-EBNA3a
市场价: ¥4200.00
美元价: 2520.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

RepliTope™EBV(EBNA3a)

ProductCode:RT-EBV-EBNA3a

Peptidemicroarraydisplaying234peptidesderivedfromapeptidescan(15merswith11aaoverlap)throughEpstein-Barrnuclearantigen3(EBNA3a)(Swiss-ProtID:P12977)ofEpstein-Barrvirus(HHV4).
Amount:1peptidemicroarray(eachpeptideisdeposited3xpersubarray,4subarraysperslide)+dummyslideandspacers(neededforincubation)
Purity:Freeoftruncatedsequences
DeliveryFormat:Peptidesimmobilizedontoglassslide(3x1inches;75by25mm)
Application(s):Immunemonitoring,Humoralimmuneresponse,SEROMarkerdiscovery,Antibodyepitopediscovery,Bindingexperiments
Indication(s)/Topic(s):Infection,Cancer,Hodgkin"slymphoma,Burkitt"slymphoma,Nasopharyngealcarcinoma,Dermatomyositis,Systemiclupuserythematosus,Rheumatoidarthritis,Sjgren"ssyndrome,Multiplesclerosis
DeliveryTime:10-12days

RepliTope™PeptideMicroarrays
JPTPeptideTechnologiesappliesitsuniquepeptidemicroarrayplatformtogeneratepeptidemicroarraysonglassslidesforbiomarkerdiscovery,immunomonitoringanddetectionandvalidationofproteininteractions.PeptidesareimmobilizedonglassslidesviaaflexIBLelinkerbychemoselectivecoupling.Thecovalentlyattachedpeptidesaredisplayedinfourcopiesoneachslide.Inaddition,multipleidenticalcopiesofeachmicroarrayareproduced.Incubationcanbeperformedmanuallyorautomatedusingonlyminimalamountsofyoursample.Read-outviafluorescenceresultsinlowbackgroundandhighsensitivity.

BenefitsofJPT"sRepliTope™PeptideMicroarrays
-Gethundredsofidenticalmicroarraycopies
-Peptidesarefreeoftruncatedsequences
-Smallamountsofyourprecioussamplesareneededforincubation
-ApplicabletoavarietyofBIOLOGicalsamples(e.g.serum,plasma,antibody)
-Lowbackgroundonglasssurface
-Read-outviafluorescence

RepliTope™EBV(EBNA3a)

SelectedReferencesforJPT"sPeptideMicroarrays
"StructureofGPN-loopGTPaseNpa3andImplicationsforRNAPolymeraseIIAssembly"
Niessertal.,MolCellBiol. (2015)-PMID:26711263
"ProtectiveEfficacyofAdenovirus-proteinVaccinesAgainstSIVChallengesinRhesusMonkeys"
Barouchetal.,Science(2015)-PMID:26138104
"IdentificationandCharacterizationofCommonBCellEpitopeinBovineLeukemiaVirusviaHigh-throughputPeptideScreeningSysteminInfectedCattle"
Baietal.,Retrovirology(2015)-PMID:26715158
"High-ThroughputMicroarrayIncubationsUsingMulti-WellChambers"
Zerwecketal.,MethodsMolBiol.(2015)-PMID:26490464
"PeptideMicroarraysforCoverageofSequenceDiversityinMonitoringtheBcellImmuneResponse(TECH2P.911)"
Castro,etal.,TheJournalofImmunology(2015)-PMID:n.a.
"AntibodiestoInfluenzaNucleoproteinCross-reactwithHumanHypocretinReceptor2"
Ahmedetal.,ScienceTranslationalMedicine(2015)-PMID:26136476
"SerumReactomeInducedbyBordetellaPertussisInfectionandPertussisVaccines:QualitativeDifferencesinSerumAntibodyRecognitionPatternsRevealedbyPeptideMicroarrayAnalysis"
Valentinietal.,BMCImmunol.(2015)-PMID:26129684

ApplicationNotes
"AModularApproachforEpitopeDiscoveryandHigh-ResolutionProfilingofHumoralImmuneResponses"
Pawlowskietal.(2013)Fulltext
"MultipleSclerosisandEpsteinBarrVirusInfection.AnEpitopeMappingStudy"
Reimeretal.(2014)Fulltext
"TheChallengeofAntigenSequenceDiversity:SolutionswithULTRAPeptideLibraries"
Pawlowskietal.(2015)Fulltext
"RapidMimotopeOptimizationforPharmacokineticAnalysisoftheNovelTherapeuticantibodyIMAB362"
Danescharetal.(2014)Fulltext

TestimonialsforJPT"sPeptideMicroarrays
"Overthepastfiveyearsmyresearchteamhasbeenactiveinthedevelopmentofspecies-specificpeptidearrays.OurABIlitytoadvancethistechnologyintonewresearchareashasbeendependentonworkingwiththehighestqualityofarrays.Inthisregard,JPT"scommitmenttoexcellencehasbeenacriticalfoundationforthesuccessofourresearchprogram.Ihavebeenconsistentlyimpressedwiththeircustomerservice,technicalexpertiseandprofessionalism.Whenitcomestopeptideworktherearenootheroptionsforourgroup,JPTisthebest."
ScottNapper,PhD,VaccineandInfectiousDiseaseOrganization(VIDO),UniversityofSaskatchewan,Canada

"TheRV144HIVtrialisconsideredasoneoffirstsuccessfulHIVvaccinetrials.IthasbecomeclearthattheV2loopofgp120isanimportantsiteforimmunogenicityandprotectionfromHIVinfection.TheuseofJPT"sPepStar™microarraytechnologyhasbeenveryusefulforthecorrelationoftheclincialoutcomewithhumoralimmuneresponses.AshavethecyclicpeptidesbeenfromJPTtovalidatethesefindings!."
JeffCurrier,PhD,WalterReedArmyInstitute,Rockville,Maryland,USA

"WestudymodulationofdopaminergicneurotransmissonbyTAAR1andD2R.ThefunctionalinteractionofthetworeceptorsinthebrainsupportsTAAR1asatargetforthetreatmentofpsychiatricdisorderssuchasschizophreniaorbipolardisorder.Tomaptheepitopesofournewlygeneratedspecificanti-ratTAAR1antibodiesweusedJPT"sPepStarTMpeptidemicroarrays.Thepeptidemicroarraysgreatlycontributedtooursuccessfulandrecentlypublishedstudy.WewereverysatisifiedwiththeexceptionalproductandservicedeliveredbyJPTPeptideTechnologiesaswellastheirscientificCustomerSupportwhichwasalwaysatourdisposal."
StefanObermüller,F.Hoffmann-LaRocheLtd.,RochePharmaResearchandEarlyDevelopment,Basel,Switzerland

RepliTope™EBV(EBNA3a)

TechnicalData:
ApplicationAntibodyepitopediscovery
Immunemonitoring
ProteinNameEpstein-Barrnuclearantigen(EBNA)
OrganismEpstein-Barrvirus(HHV-4)
Indication/TopicAutoimmunedisease
Burkitt"slymphoma
Hodgkin"slymphoma
Nasopharyngealcarcinoma
Numberofpeptides234 

FurtherInformation:
Amount1peptidemicroarray(eachpeptideisdeposited3xpersubarray,4subarraysperslide)+dummyslideandspacers(neededformanualincubation)
SpecificationsPeptidescan(15merswith11aaoverlap)
DocumentationCDwithProtocol,Datasheet,gal-fileandgal-viewer
Swiss-ProtID
P12977
NCBIYP_401669 
SequenceMDKDRPGPPALDDNMEEEVPSTSVVQEQ
VSAGDWENVLIELSDSSSEKEAEDAHLE
PAQKGTKRKRVDHDAGGSAPARPMLPPQ
PDLPGREAILRRFPLDLRTLLQAIGAAA
TRIDTRAIDQFFGSQISNTEMYIMYAMA
IRQAIRDRRRNPASRRDQAKWRLQTLAA
GWPMGYQAYSSWMYSYTDHQTTPTFVHL
QATLGCTGGRRCHVTFSAGTFKLPRCTP
GDRQWLYVQSSVGNIVQSCNPRYSIFFD
YMAIHRSLTKIWEEVLTPDQRVSFMEFL
GFLQRTDLSYIKSFVSDALGTTSIQTPW
IDDNPSTETAQAWNAGFLRGRAYGIDLL
RTEGEHVEGATGETREESEDTESDGDDE
DLPCIVSRGGPKVKRPPIFIRRLHRLLL
MRAGKRTEQGKEVLEKARGSTYGTPRPP
VPKPRPEVPQSDETATSHGSAQVPEPPT
IHLAAQGMAYPLHEQHGMAPCPVAQAPP
TPLPPVSPGDQLPGVFSDGRVACAPVPA
PAGPIVRPWEPSLTQAAGQAFAPVRPQH
MPVEPVPVPTVALERPVYPKPVRPAPPK
IAMQGPGETSGIRRARERWRPAPWTPNP
PRSPSQMSVRDRLARLRAEAQVKQASVE
VQPPQLTQVSPQQPMEGPLVPEQQMFPG
APFSQVADVVRAPGVPAMQPQYFDLPLI
QPISQGAPVAPLRASMGPVPPVPATQPQ
YFDIPLTEPINQGASAAHFLPQQPMEGP
LVPEQWMFPGAALSQSVRPGVAQSQYFD
LPLTQPINHGAPAAHFLHQPPMEGPWVP
EQWMFQGAPPSQGTDVVQHQLDALGYTL
HGLNHPGVPVSPAVNQYHLSQAAFGLPI
DEDESGEGSDTSEPCEALDLSIHGRPCP
QAPEWPVQEEGGQDATEVLDLSIHGRPR
PRTPEWPVQGEGGQNVTGPETRRVVVSA
VVHMCQDDEFPDLQDPPDEA
ProteinLength(aa)944
品牌介绍
JPT的关键技术平台基于该公司强大而长期的技术,化学和生物学背景。JPT已经开发了几种独特的方法,可解决细胞疗法和疫苗开发过程的所有阶段,包括生物标记物发现,新表位优先,免疫监测和疫苗功效测试。此外,这四个技术平台为靶向蛋白质组学和分子诊断奠定了基础。JPT的技术在需要进行肽筛查的领域中得到了广泛的应用。典型示例包括:筛选蛋白肽,酶活性(蛋白酶,激酶,磷酸酶,甲基转移酶)或肽前导结构的系统优化。